Anthony Anderson was first seen in the Episode: "Nanna Don't Play" of the American sitcom āIn the Houseā in 1995. The following year, he joined the cast of the American teen sitcom āHang Timeā as āTheodore "Teddy" Brodis, Jr.ā He starred in 39 episodes and parted ways from the show in 1998. He made his big-screen debut in the 1999 American comedy-drama film āLiberty Heightsā directed by Barry Levinson. The film received a positive response from critics and holds an 85% approval rating on Rotten Tomatoes. In 2000, he starred as āMauriceā in the American action film āRomeo Must Dieā directed by Andrzej Bartkowiak. While the film opened to a mixed reception, it was a box office success and grossed over $91 million on a $25 million budget. That same year, he also played the role of āNolanā in the American crime comedy film āBig Momma's Houseā directed by Raja Gosnell. The film received negative reviews from critics but turned out to be a box office success. He next starred in films like āSee Spot Runā (2001), āExit Woundsā (2001), āKingdom Comeā (2001), āBarbershopā (2002), āKangaroo Jackā (2003), āMalibu's Most Wantedā (2003), āHarold & Kumar Go to White Castleā (2004), āKing's Ransomā (2005), āHoodwinked!ā (2005), āScary Movie 4ā (2006), āThe Departedā (2006), and āTransformersā (2007).Ā
In 2008, he grabbed the role of āDetective Kevin Bernardā in the American police procedural and legal drama television series āLaw & Orderā created by āDick Wolf.ā He remained a part of the show until it went off-air in 2010. However, he made a special appearance on the show after its revival in 2022. He continued to appear in television series and shows such as āSamantha Whoā (2008), āShamelessā (2011), āPsychā (2012), āGuys with Kidsā (2012-2013), and āHollywood Game Nightā (2013-2014). In 2014, he became a part of the main cast of the American sitcom television series āBlack-ishā where he starred as āAndre "Dre" Johnson.ā The show ran for 8 seasons and aired its final episode in 2022. He next appeared in television shows like āCarnival Cravings with Anthony Andersonā (2015), āTo Tell the Truthā (2016-present), āThe Gong Showā (2017), āDrop the Micā (2017), āGrown-ishā (2018), āMixed-ishā (2019), and āExtreme Makeover: Home Editionā (2020). In 2020, he made an appearance on the American television game show āWho Wants to Be a Millionaire.ā