Krysten Ritter was first seen in the 2001 Tony Goldwyn-directed American romantic comedy film ‘Someone like You’ where she made an uncredited appearance as a model. The film received a lukewarm response from critics and has a 42% approval rating on Rotten Tomatoes. Following her debut, she went on to star in films like ‘Garmento’ (2002), ‘Mona Lisa Smile’ (2003), ‘Slingshot’ (2005), ‘Heavy Petting’ (2007), ‘27 Dresses’ (2008), and ‘What Happens in Vegas’ (2008). In 2009, she starred as ‘Suze Cleath-Stuart’ in the American romantic comedy film ‘Confessions of a Shopaholic’ directed by P. J. Hogan. The film, despite being by panned by critics, managed to gross over $108.3 million at the box office. That same year, she also joined the cast of the American neo-Western crime drama television series ‘Breaking Bad’ created by Vince Gilligan. She played the role of ‘Jane Margolis’ and remained a part of the show until 2010. She next appeared in the 2010 American romantic comedy film ‘She's Out of My League’ directed by Jim Field Smith. The film received a mixed response from critics and sits on a 58% approval rating on Rotten Tomatoes.
She next starred in films like ‘Killing Bono’ (2011), ‘Life Happens’ (2011), ‘Vamps’ (2012), ‘Refuge’ (2012), ‘Listen Up Philip’ (2014), ‘Veronica Mars’ (2014), and ‘Big Eyes’ (2014). In 2015, she joined the lead cast of the American television series ‘Jessica Jones’ created by Melissa Rosenberg. The series ran for 3 seasons and aired its final episode in 2019. Her portrayal of ‘Jessica Jones’ in the show earned her a ‘Saturn Award’ nomination. She was last seen in the 2021 American dark fantasy film ‘Nightbooks’ directed by David Yarovesky. The film opened to a positive reception and received an 87% approval rating on Rotten Tomatoes.