Brittany Snow made her debut in the 1995 Japanese animated musical coming-of-age romantic drama film ‘Whisper of the Heart’ where she voiced ‘Shizuku Tsukishima’ (2006 English dub). In 1998, she became a part of the American radio and television soap opera ‘Guiding Light’ created by Irna Phillips and Emmons Carlson. She played the role of Susan "Daisy" Lemay and remained a part of the show until 2002. She was next seen in television series like ‘Safe Harbor’ (1999) and ‘American Dreams’ (2005-2005). Snow starred as ‘Marcia Prentiss Shaw’ in the 2004 American neo-noir psychological political thriller film ‘The Manchurian Candidate’ directed by Jonathan Demme. The film received mostly positive reviews from critics and earned an 80% approval score on Rotten Tomatoes. The following year, she played the role of ‘Zoe Plummer’ in the Adam Shankman-directed American family action comedy film ‘The Pacifier.’ Despite opening to negative reception, the film managed to gross over $198.6 million on a budget of $56 million. She next appeared in the 2006 American teen romantic comedy film ‘John Tucker Must Die’ directed by Betty Thomas. The film received a sort of lukewarm response from critics but managed to gross over $68.8 million on a budget of $18 million.
She continued to star in films like ‘Hairspray’ (2007), ‘On the Doll’ (2007), ‘Finding Amanda’ (2008), ‘Prom Night’ (2008), ‘The Vicious Kind’ (2009), ‘Black Water Transit’ (2009), ‘Janie Jones’ (2010), ‘96 Minutes’ (2011), ‘Petunia’ (2012), ‘Pitch Perfect’ (2012), ‘Syrup’ (2013), ‘There's Always Woodstock’ (2014), ‘Pitch Perfect 2’ (2015), ‘The Late Bloomer’ (2016), ‘Hangman’ (2017), ‘Pitch Perfect 3’ (2017), ‘Someone Great’ (2019), and ‘Hooking Up’ (2020). She was last seen in the 2022 American slasher film ‘X’ directed by Ti West. The film was widely praised by critics and received a 96% approval rating on Rotten Tomatoes.