Bill Murray first appeared in the American television variety show ‘Saturday Night Live with Howard Cosell’ in 1975. He went on to make his big-screen debut in the 1976 American comedy-drama film ‘Next Stop, Greenwich Village’ where he made an uncredited appearance as ‘Nick Kessel.’ In 1979, he starred as ‘Tripper Harrison’ in the Ivan Reitman-directed Canadian comedy film ‘Meatballs.’ The film received mostly positive reviews from critics and was a massive box office success, grossing over $1.6 million on a budget of $70 million. He was next seen in films like ‘Where the Buffalo Roam’ (1980), ‘Caddyshack’ (1980), ‘Loose Shoes’ (1980), ‘Stripes’ (1981), and ‘Tootsie’ (1982). In 1984, he portrayed Dr. Peter Venkman in the American supernatural comedy film ‘Ghostbusters’ directed by Ivan Reitman. The film opened to massive critical acclaim and was a major box office hit, having grossed over $295.2 million on a $25–30 million budget. Murray also received a Golden Globe Award nomination for his performance in the film. That same year, he also appeared in the American drama film ‘The Razor's Edge’ directed by John Byrum. The film received a lukewarm response from critics. He next starred in films like ‘Little Shop of Horrors’ (1986), ‘Scrooged’ (1988), ‘Ghostbusters II’ (1989), ‘Quick Change’ (1990), ‘What About Bob?’ (1991), ‘Groundhog Day’ (1993), ‘Ed Wood’ (1994), ‘Kingpin’ (1996), ‘Space Jam’ (1996), ‘The Man Who Knew Too Little’ (1997), ‘Wild Things’ (1998), ‘With Friends Like These…’ (1998), ‘Cradle Will Rock’ (1999), ‘Charlie's Angels’ (2000), ‘Osmosis Jones’ (2001), and ‘The Royal Tenenbaums’ (2001).
In 2003, he portrayed Bob Harris in the romantic comedy-drama film ‘Lost in Translation’ directed by Sofia Coppola. The film was lauded by critics and did decent business at the box office, grossing over $118.7 million on a $4 million budget. Murray also became a recipient of the ‘British Academy Film Award’ and ‘Golden Globe Award’ along with an Academy Award nomination for his performance in the film. The following year, he voiced ‘Garfield’ in the American live-action/computer-animated comedy film ‘Garfield: The Movie’ directed by Peter Hewitt. Despite the film being largely panned by critics, it managed to gross over $203.2 million on a budget of $50 million. That same year, he also starred in the American comedy-drama film ‘The Life Aquatic with Steve Zissou’ directed by Wes Anderson. The film opened to a mixed critical reception and was a commercial failure. He was seen in films like ‘Broken Flowers’ (2005), ‘Garfield: A Tail of Two Kitties’ (2006), ‘City of Ember’ (2008), ‘The Limits of Control’ (2009), ‘Get Low’ (2010), ‘Passion Play’ (2011), ‘Hyde Park on Hudson’ (2012), ‘The Monuments Men’ (2014), ‘St. Vincent’ (2014), ‘Aloha’ (2015), ‘The Jungle Book’ (2016), ‘Ghostbusters’ (2016), ‘Isle of Dogs’ (2018), ‘The Dead Don't Die’ (2019), ‘On the Rocks’ (2020), and ‘The French Dispatch’ (2021). He was last seen in the 2021 American supernatural comedy film ‘Ghostbusters: Afterlife’ directed by Jason Reitman. The film received mixed reviews from critics and was a financial success. He is all set to appear in the upcoming American superhero film ‘Ant-Man and the Wasp: Quantumania.’