American actress Lucy DeVito portrayed the main character in the lead role of the play Anne Frank at the Intiman Theatre in Seattle, Washington in 2008. She is the daughter of actor Danny DeVito and actress Rhea Periman. Her first major role in a motion picture was as Anne Greenstein in the movie ‘Leaves of Grass’ (2010). She played the role of the daughter of her real life father in the movie 'The Comedian’ (2016). Her other movies include ‘A Quiet Little Marriage’ (2008), ‘Speech & Debate’ (2017), ‘Rich Boy – Rich Girl’ (2019) and ‘Dumbo’ (2019). Her role as Cindy in the movie ‘Syrup’ (2013) received negative reviews.
DeVito received positive reviews for her role as Jenny Woman in the television series ‘It’s Always Sunny in Philadelphia’ (2006 -2007). She also appeared in the television series ‘Dirt’ (2007), ‘Melissa & Joey’ (2010 – 2012) and ‘Deadbeat’ (2014 – 2016). In 2017 she acted in the romantic comedy play ‘Hot Mess’ and gained appreciation of the audience.