Cote de Pablo was first seen on-screen at the age of fifteen when she hosted few episodes of a talk show, ‘Control.’ She then appeared in ‘All My Children,’ a TV show; picked up roles in New York City Public Theatre, and also appeared in commercials. She starred in ‘The Jury,’ a legal drama television series where she portrayed Marguerite Cisneros. She then appeared in ‘NCIS,’ an action police procedural television series where she portrayed Ziva David and for which she earned an ‘ALMA Award.’
Some of her other notable television and film roles include ‘The Dovekeepers,’ ‘The $treet,’ ‘The Last Rites of Ransom Pride,’ ‘The Education of Max Bickford,’ ‘The 33,’ and ‘Prototype.’ She has also lent her voice to the character of Melanie Sanchez in video game ‘TOCA Race Driver.’