Luke Goss first appeared in the 2000 two-part British television crime drama mini-series ‘The Stretch,’ directed by Frank W. Smith. The series earned a 7.3 out of 10 rating on IMDb. That same year, he also made his big-screen debut in the Simon Monjack-directed drama film ‘Two Days, Nine Lives,’ where he played the role of ‘Saul.’ In 2002, he starred as ‘Jared Nomak’ in the American superhero film ‘Blade II,’ directed by Guillermo del Toro. Even though the film opened to a mixed reception, it managed to gross over $155 million on a budget of $54 million. That same year, he also played the role of ‘Cadillac Tom’ in the David S. Goyer-directed American comedy-drama film ‘Zig Zag.’ The film holds a 44% approval rating on Rotten Tomatoes. In 2004, he portrayed ‘The Creature’ in the American television miniseries ‘Frankenstein,’ directed by Kevin Connor. The series received mostly positive reviews from critics. The same year also saw the release of the Hong Kong superhero film ‘Silver Hawk,’ directed by Jingle Ma. The film grossed over HK$3.3 million at the box office. He next starred as ‘Joey Trent/Kane’ in the 2005 Les Mayfield-directed American buddy cop comedy film ‘The Man.’ The film was largely panned by critics and was a commercial failure.
In 2006, he portrayed ‘King Xerxes’ in the American religious epic film ‘One Night with the King,’ directed by Michael O. Sajbel. The film opened to mostly negative reviews and failed to perform at the box office. It currently holds a 19% approval rating on Rotten Tomatoes. He continued to star in films like ‘Mercenary for Justice’ (2006), ‘Bone Dry’ (2007), ‘Shanghai Baby’ (2007), and ‘Unearthed’ (2007). In 2008, he played the role of ‘Prince Nuada’ in the American superhero film ‘Hellboy II: The Golden Army,’ directed by Guillermo del Toro. The film garnered praise from critics and grossed over $168.3 million on a budget of $82.5–85 million. Goss was next seen in films and television series like ‘Fringe’ (2009), ‘Tekken’ (2009), ‘Witchville’ (2010), ‘Across the Line: The Exodus of Charlie Wright’ (2010), ‘Death Race 2’ (2010), ‘Seven Below’ (2011), ‘Blood Out’ (2011), ‘Interview with a Hitman’ (2012), ‘Death Race 3: Inferno’ (2013), ‘Red Widow’ (2013), ‘Dead Drop’ (2014), ‘War Pigs’ (2015), ‘Operator’ (2015), ‘Killing Salazar’ (2016), and ‘Mississippi Murder’ (2017).
He portrayed ‘Red’ in the American horror-thriller film ‘Traffik,’ directed by Deon Taylor. The film failed to impress critics and received a 27% approval score on Rotten Tomatoes. He next starred in films like ‘The Last Boy’ (2019), ‘The Hard Way’ (2019), ‘Hollow Point’ (2019), ‘Legacy’ (2020), ‘Paydirt’ (2020), and ‘The Loss Adjuster’ (2020). He was last seen playing the role of ‘David’ in the 2021 sci-fi crime-thriller film ‘R.I.A.’ directed by Richard Colton.