Imogen Poots was first seen playing the role of ‘Alice Thornton’ in the Episode: "Love Bites" of the British medical drama series ‘Casualty’ in 2004. She made her film debut in the James McTeigue-directed 2005 dystopian political action film ‘V for Vendetta.’ The film received a favorable response from critics and was a commercial success. In 2007, she starred as ‘Tammy’ in the post-apocalyptic horror film ‘28 Weeks Later’ directed by Juan Carlos Fresnadillo. The film garnered praise from critics and did decent business at the box office. The following year, she was seen playing the role of ‘Lorelei Lathrop’ in the period drama film ‘Me and Orson Welles’ directed by Richard Linklater. The film opened to positive reviews and was later named one of the top ten independent films of the year by the National Board of Review. She next appeared in films such as ‘Cracks’ (2009), ‘Waking Madison’ (2009), ‘Solitary Man’ (2009), ‘Centurion’ (2010), ‘Chatroom’ (2010), and ‘Jane Eyre’ (2011).Â
In 2011, she starred as ‘Amy Peterson’ in the American horror comedy film ‘Fright Night’ directed by Craig Gillespie. The film received a positive response from critics who praised the performance of the cast. The following year, she was seen in the Yaron Zilberman-directed American drama film ‘A Late Quartet.’ The film saw its premiere at the 2012 Toronto International Film Festival and garnered positive reviews upon release. The year 2013 saw the release of the biographical drama film ‘Jimi: All Is by My Side’ where Poots portrayed ‘Linda Keith.’ The film saw mostly positive reviews upon release and gained an approval rating of 67% on Rotten Tomatoes. In 2014, she was seen in the action thriller film ‘Need for Speed’ directed by Scott Waugh. Even though the film was panned by critics, it did decent business at the box office. Poots continued to star in films like ‘Knight of Cups’ (2015), ‘A Country Called Home’ (2015), ‘Frank & Lola’ (2016), ‘Killing for Love’ (2016), ‘Sweet Virginia’ (2017), ‘I Kill Giants’ (2017), ‘Age Out’ (2018), ‘The Art of Self-Defense’ (2019), ‘Vivarium’ (2019), and ‘Black Christmas’ (2019). She was last seen in the 2020 black comedy-drama film ‘French Exit’ directed by Azazel Jacobs. The film received mixed to positive reviews from critics.