Tamzin Merchant made her screen debut in the 2005 Joe Wright-directed romantic drama film ‘Pride & Prejudice,’ where she portrayed ‘Georgiana Darcy.’ The film opened to a positive critical reception and received 4 ‘Academy Award’ nominations. It was also a financial success and grossed over $121.6 million on a $28 million budget. That same year, she also starred as ‘Margo Durrell’ in the television film ‘My Family and Other Animals,’ directed by Sheree Folkson. The film holds an 82% audience score on Rotten Tomatoes. She next starred in films like ‘The Good Housekeeping Guide’ (2006), ‘Casualty 1906’ (2006), ‘Radio Cape Cod’ (2008), ‘Bonekickers’ (2008), and ‘Princess Kaiulani’ (2009). In 2009, she joined the cast of the historical fiction television series ‘The Tudors,’ created by Michael Hirst. She played the role of ‘Catherine Howard’ and remained a part of the series until it went off-air in 2010. She next portrayed ‘Mary Rivers’ in the 2011 romantic drama film ‘Jane Eyre,’ directed by Cary Joji Fukunaga. The film garnered praise from critics and received an 84% approval rating on Rotten Tomatoes. She was next seen in television series and films like ‘Red_Faction: Origins’ (2011), ‘DCI Banks’ (2011), ‘Second Wind’ (2012), ‘The Mystery of Edwin Drood’ (2012), and ‘Murder on the Home Front’ (2013).
In 2014, she starred as ‘Sandra’ in the Canadian-American coming-of-age adventure film ‘Copenhagen,’ directed by Mark Raso. The film received a favorable response from critics and holds an 88% approval rating on Rotten Tomatoes. That same year, she also became a part of the American supernatural horror television series ‘Salem’ where she grabbed the role of ‘Anne Hale.’ The series ran for 3 seasons and aired its final episode in 2017. Merchant next appeared in the 2015 fantasy adventure film ‘Dragonheart 3: The Sorcerer's Curse’ directed by Colin Teague. The film received a mixed response from critics. That same year, she portrayed the role of ‘Sarah’ in the David Blair-directed British supernatural mystery horror film ‘The Messenger.’ The film holds a 33% approval score on Rotten Tomatoes. She continued to star in films and television series such as ‘The Dancer’ (2016), ‘Dragonheart: Battle for the Heartfire’ (2017), ‘Supergirl’ (2017), ‘Carnival Row’ (2019), and ‘Thanks for the Memories’ (2019). Merchant was last seen in the 2020 comedy-drama film ‘Running Naked,’ directed by Victor Buhler. The film has a 5.4 out of 10 rating on IMDb.