Alyssa Milano made her screen debut in the 1984 American comedy-drama coming-of-age film ‘Old Enough’ directed by Marisa Silver. The film currently holds a 6.3 out of 10 rating on IMDb. That same year, she also joined the lead cast of the American sitcom television series ‘Who's the Boss?’ as ‘Samantha Micelli.’ The series ran for 8 seasons and aired its final episode in 1992. Milano also won 2 ‘Young Artist Awards’ and 3 ‘Kids' Choice Awards’ for her portrayal of Samantha Micelli in the series. In 1985, she starred as ‘Jenny Matrix’ in the American action film ‘Commando’ directed by Mark L. Lester. The film opened to a mixed reception but managed to emerge as a commercial success, grossing over $57.5 million on a budget of $9 million. She continued to star in films such as ‘Speed Zone’ (1989), ‘Where the Day Takes You’ (1992), ‘Little Sister’ (1992), ‘Conflict of Interest’ (1993), ‘Double Dragon’ (1994), ‘Embrace of the Vampire’ (1995), ‘Glory Daze’ (1995), ‘Deadly Sins’ (1995), ‘Poison Ivy II: Lily’ (1996), ‘Fear’ (1996), ‘Public Enemies’ (1996), ‘Below Utopia’ (1997), and ‘Hugo Pool’ (1997). In 1998, she grabbed the role of ‘Phoebe Halliwell’ in the American fantasy drama television series ‘Charmed’ created by Constance M. Burge. The series aired 178 episodes in a span of 8 seasons before going off-air in 2006.Â
Milano was next seen in television films and series like ‘The Diamond Hunters’ (2001), ‘The Adventures of Jimmy Neutron: Boy Genius’ (2004), ‘My Name Is Earl’ (2007-2008), ‘Wisegal’ (2008), ‘Castle’ (2010), ‘Romantically Challenged’ (2010-2011), ‘Breaking In’ (2011-2012), ‘Mistresses’ (2013-2014), ‘Hollywood Game Night’ (2014), ‘Rupaul's Drag Race’ (2015), and ‘Wet Hot American Summer: Ten Years Later’ (2017). In 2018, she starred as ‘Dora’ in the Canadian-American romantic comedy film ‘Little Italy’ directed by Donald Petrie. The film was largely panned by critics and received a 13% approval score on Rotten Tomatoes. She next appeared in television series and films such as ‘Insatiable’ (2018-2019), ‘Tempting Fate’ (2019), ‘Grey's Anatomy’ (2019), ‘Celebrity Call Center’ (2020), ‘You Are My Home’ (2020), and ‘The Now’ (2021). She was last seen playing the role of ‘Grace’ in the 2022 American thriller film ‘Brazen’ directed by Monika Mitchell. The film holds an 18% approval rating on Rotten Tomatoes.