Selma Blair first appeared in the Episode: "Das Bus" of the American comedy television series ‘The Adventures of Pete & Pete’ in 1995. She went on to make her big-screen debut in the 1996 comedy romance film ‘The Broccoli Theory’ directed by Brent Sterling Nemetz. That same year, she also appeared in the Canadian comedy film ‘Kids in the Hall: Brain Candy’ directed by Kelly Makin. The film received a mixed response from critics and scored a 43% approval rating on Rotten Tomatoes. She was next seen in films like ‘Strong Island Boys’ (1997), ‘Arresting Gena’ (1997), ‘In & Out’ (1997), ‘Brown's Requiem’ (1998), ‘Girl’ (1998), ‘Cruel Intentions’ (1999), ‘Down to You’ (2000), and ‘Storytelling’ (2001). In 2001, she starred as ‘Vivian Thelma Kensington’ in the American comedy film ‘Legally Blonde’ directed by Robert Luketic. The film received mixed to positive reviews from critics but was a major box office success and grossed over $141.8 million on an $18 million budget. The following year, she was seen playing the role of ‘Jane Burns’ in the Roger Kumble-directed American comedy film ‘The Sweetest Thing.’ The film was panned by critics and received a 26% approval rating on Rotten Tomatoes.Â
After appearing in films like ‘A Guy Thing’ (2003) and ‘Dallas 362’ (2003), Blair portrayed Liz Sherman in the 2004 American superhero film ‘Hellboy’ directed by Guillermo del Toro. The film received a positive response from critics and grossed over $99.8 million on a budget of $60–66 million. That same year, she also starred in the American satirical sex comedy film ‘A Dirty Shame’ directed by John Waters. The film opened to a mixed reception and was a box office failure. Blair continued to star in films like ‘Pretty Persuasion’ (2005), ‘The Fog’ (2005), ‘The Alibi’ (2006), ‘The Night of the White Pants’ (2006), ‘Hellboy: Sword of Storms’ (2006), ‘Hellboy: Blood and Iron’ (2007), ‘Purple Violets’ (2007), ‘Hellboy II: The Golden Army’ (2008), ‘The Family Tree’ (2011), ‘Dark Horse’ (2011), ‘Columbus Circle’ (2012), ‘Sex, Death and Bowling’ (2015), ‘Ordinary World’ (2016), ‘Mom and Dad’ (2017), ‘After’ (2019), ‘A Dark Foe’ (2020), and ‘After We Collided’ (2020). She was last seen in the 2021 comedy-drama film ‘Far More’ directed by Ally Walker.