Marika Domińczyk first appeared in the Episode: "Closet Cases" of the American drama television series ‘The Street’ in 2000. The following year, she made her silver screen debut in the Lee Davis-directed crime film ‘3 A.M.’ where she played the role of ‘Cathy.’ In 2005, she starred as ‘Bernadette’ in the American romantic comedy film ‘The 40-Year-Old Virgin’ directed by Judd Apatow. The film received a favorable response from critics and also performed well at the box office, grossing over $177.4 million on a budget of $26 million. In 2006, she joined the cast of the American family drama television series ‘Brothers & Sisters’ as ‘Tyler Altamirano.’ The series aired 109 episodes in a span of 5 seasons before going off-air in 2011. Domińczyk continued to appear in television series and shows such as ‘Las Vegas’ (2008), ‘House’ (2008), ‘The Unit’ (2009), ‘Rizzoli & Isles’ (2011), ‘Vegas’ (2013), and ‘Criminal Minds’ (2013). She next played the role of ‘Amanda’ in the 2014 American black comedy film ‘Let's Kill Ward's Wife’ directed by Scott Foley. The film received mostly negative reviews from critics and holds a 17% approval rating on Rotten Tomatoes. In 2016, she became a part of the American medical drama television series ‘Grey's Anatomy’ created by Shonda Rhimes. She played the role of ‘Dr. Eliza Minnick’ and remained a part of the show until 2017. She next appeared in television shows like ‘Whiskey Cavalier’ (2019), ‘Hawaii Five-0’ (2020), and ‘Inventing Anna’ (2022). She was last seen playing the role of ‘Ana’ in the American black comedy crime drama thriller television series ‘Barry’ in 2022.
