Daniel Tosh made his screen debut in the American crime drama television series, ‘Sins of the City’ in 1998. In 2003, he appeared in the American stand-up comedy television series Comedy Central Presents.’ The following year, he played the role of a criminal in Episode: "3.6" of the American hidden camera–practical joke reality television series ‘Punk'd.’ He was next seen in television series and shows such as ‘Daniel Tosh: Completely Serious’ (2007), ‘The Love Guru’ (2008), ‘Live at Gotham’ (2008), and ‘The Life & Times of Tim’ (2008). In 2009, he came together with Mike Gibbons and created the American television series ‘Tosh.0.’ The show aired 301 episodes in a span of 12 seasons before going off-air in 2020. In 2011, he released his third comedy album titled ‘Happy Thoughts.’ That same year, he also made an appearance in the comedy show ‘Dave's Old Porn.’ In 2012, he joined the voice cast of the American adult animated sitcom ‘Brickleberry’ where he voiced ‘Malloy.’ The show ran for 3 seasons and aired its final episode in 2015. However, he briefly returned to the show in 2020 and appeared in the Episode: "Paradise PD Meets Brickleberry."